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Retroperitoneal Mature Cystic Teratoma in a 3-month-old Infant: A Case Report and Literature Review
CC BY-NC-ND 4.0 · Indian J Med Paediatr Oncol 2019; 40(02): 304
DOI: DOI: 10.4103/ijmpo.ijmpo_34_18
Sir,
I read the interesting case report by Tripathy et al. on the retroperitoneal mature cystic teratoma (RPMCT) in a 3-month-old Indian infant.[1] It is well-known that children with perinatal exposure to human immunodeficiency virus (HIV) are more vulnerable to various tumors compared to nonexposed counterparts.[2] To my knowledge, HIV infection is a worrisome health hazard in India. Although no recent data are yet present on the pediatric HIV seroprevalence, the available data pointed out to the substantial HIV seroprevalence rate of 1.03% among pregnant in India.[3] The HIV status of the mother of the studied infant was regrettably not determined. I presume that some form of vertical HIV transmission needed to be expected in the studied infant. Hence, contemplating the diagnostic battery of CD4 lymphocyte count and viral overload measurements was envisaged in the studied infant. If that diagnostic battery was conducted and it showed HIV infection, the case in question could be truly considered a novel case report in India. This is because HIV-associated RPMCT has never been reported in the pediatric literature so far.
Publication History
Article published online:
03 June 2021
© 2019. Indian Society of Medical and Paediatric Oncology. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).
Thieme Medical and Scientific Publishers Pvt. Ltd.
A-12, 2nd Floor, Sector 2, Noida-201301 UP, India
Sir,
I read the interesting case report by Tripathy et al. on the retroperitoneal mature cystic teratoma (RPMCT) in a 3-month-old Indian infant.[1] It is well-known that children with perinatal exposure to human immunodeficiency virus (HIV) are more vulnerable to various tumors compared to nonexposed counterparts.[2] To my knowledge, HIV infection is a worrisome health hazard in India. Although no recent data are yet present on the pediatric HIV seroprevalence, the available data pointed out to the substantial HIV seroprevalence rate of 1.03% among pregnant in India.[3] The HIV status of the mother of the studied infant was regrettably not determined. I presume that some form of vertical HIV transmission needed to be expected in the studied infant. Hence, contemplating the diagnostic battery of CD4 lymphocyte count and viral overload measurements was envisaged in the studied infant. If that diagnostic battery was conducted and it showed HIV infection, the case in question could be truly considered a novel case report in India. This is because HIV-associated RPMCT has never been reported in the pediatric literature so far.
Conflict of Interest
There are no conflicts of interest.
- Tripathy PK, Pattnaik K, Jena PK, Mohanty HK. Retroperitoneal mature cystic teratoma in a 3-month-old infant: A case report and literature review. Indian J Med Paediatr Oncol 2018; 39: 117-9
- Kest H, Brogly S, McSherry G, Dashefsky B, Oleske J, Seage 3rd GR. et al. Malignancy in perinatally human immunodeficiency virus-infected children in the United States. Pediatr Infect Dis J 2005; 24: 237-42
- Sibia P, Mohi MK, Kumar A. Seroprevalence of human immunodeficiency virus among antenatal women in one of the institute of Northern India. J Clin Diagn Res 2016; 10: QC08-9
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Publication History
Article published online:
03 June 2021
© 2019. Indian Society of Medical and Paediatric Oncology. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).
Thieme Medical and Scientific Publishers Pvt. Ltd.
A-12, 2nd Floor, Sector 2, Noida-201301 UP, India
- Tripathy PK, Pattnaik K, Jena PK, Mohanty HK. Retroperitoneal mature cystic teratoma in a 3-month-old infant: A case report and literature review. Indian J Med Paediatr Oncol 2018; 39: 117-9
- Kest H, Brogly S, McSherry G, Dashefsky B, Oleske J, Seage 3rd GR. et al. Malignancy in perinatally human immunodeficiency virus-infected children in the United States. Pediatr Infect Dis J 2005; 24: 237-42
- Sibia P, Mohi MK, Kumar A. Seroprevalence of human immunodeficiency virus among antenatal women in one of the institute of Northern India. J Clin Diagn Res 2016; 10: QC08-9