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Myroides and Neurology: An Overview
CC BY-NC-ND 4.0 · Indian J Med Paediatr Oncol 2020; 41(03): 439-440
DOI: DOI: 10.4103/ijmpo.ijmpo_219_19
Sir,
We read the article, “Myroides odoratus central nervous infection in a postneurosurgery patient” on the esteemed “Indian Journal of Medical and Paediatric Oncology” with great interest. Bhat et al. reported a case of meningitis secondary to M. odoratus followed by supratentorial craniotomy due to a recurrent right frontal malignant brain tumor that arises from astrocytes.[1]
M. odoratus and Myroides odoratimimus are two important species of the Flavobacteriales order that cause infections in humans.[2] In this context, pericardial effusion, pericarditis, pneumonia, soft tissue infection, septic shock, and urinary tract infection were already associated with these microorganisms. However, neurological infections were rarely reported in literature.[3]
Here, we would like to provide a comparison between the two causes already published in the literature [Table 1].[1],[4] An interesting fact to be highlighted is that even though Myroides species infections are one of more resistant organisms in literature, in majority of the reports the individuals had full recovery.[3]
|
References |
Macfarlane et al |
Bhat et al |
|---|---|---|
|
API – Analytical profile index |
||
|
Year, country |
1985, Jamaica |
2019, India |
|
Age/sex |
6 weeks/male |
37 years/female |
|
Comorbidities |
Prematurity |
Anaplastic astrocytoma in the right frontal lobe |
|
Central nervous system infection |
Meningitis (hydrocephalus and ventriculitis) |
Meningitis following supratentorial craniotomy |
|
Microorganism identified |
Not clearly specified. It is described as Flavobacterium odoratum |
Myroides odoratus |
|
Performing tests for organism identification |
Standard biochemical tests and API 2oE |
VITEK (BioMerieux, Marcyl’Etoile, France) automated identification system and desferrioxamine (250 pgdisc) susceptibility testing |
|
Management |
First intravenous with penicillin and gentamicin. After no improvement, intraventricular cefotaxime was started |
Vancomycin and cefoperazone-sulbactam. After susceptibility results, vancomycin was withdrawn |
|
Follow-up |
Full recovery |
Full recovery of the infection |
Sir,
We read the article, “Myroides odoratus central nervous infection in a postneurosurgery patient” on the esteemed “Indian Journal of Medical and Paediatric Oncology” with great interest. Bhat et al. reported a case of meningitis secondary to M. odoratus followed by supratentorial craniotomy due to a recurrent right frontal malignant brain tumor that arises from astrocytes.[1]
M. odoratus and Myroides odoratimimus are two important species of the Flavobacteriales order that cause infections in humans.[2] In this context, pericardial effusion, pericarditis, pneumonia, soft tissue infection, septic shock, and urinary tract infection were already associated with these microorganisms. However, neurological infections were rarely reported in literature.[3]
Here, we would like to provide a comparison between the two causes already published in the literature [Table 1].[1],[4] An interesting fact to be highlighted is that even though Myroides species infections are one of more resistant organisms in literature, in majority of the reports the individuals had full recovery.[3]
|
References |
Macfarlane et al |
Bhat et al |
|---|---|---|
|
API – Analytical profile index |
||
|
Year, country |
1985, Jamaica |
2019, India |
|
Age/sex |
6 weeks/male |
37 years/female |
|
Comorbidities |
Prematurity |
Anaplastic astrocytoma in the right frontal lobe |
|
Central nervous system infection |
Meningitis (hydrocephalus and ventriculitis) |
Meningitis following supratentorial craniotomy |
|
Microorganism identified |
Not clearly specified. It is described as Flavobacterium odoratum |
Myroides odoratus |
|
Performing tests for organism identification |
Standard biochemical tests and API 2oE |
VITEK (BioMerieux, Marcyl’Etoile, France) automated identification system and desferrioxamine (250 pgdisc) susceptibility testing |
|
Management |
First intravenous with penicillin and gentamicin. After no improvement, intraventricular cefotaxime was started |
Vancomycin and cefoperazone-sulbactam. After susceptibility results, vancomycin was withdrawn |
|
Follow-up |
Full recovery |
Full recovery of the infection |
References
- Bhat VG, Vira HJ, Shetty P, Gupta S. Myroides odoratus central nervous infection in a postneurosurgery patient. Indian J Med Paediatr Oncol 2019; 40: 291-3
- Vancanneyt M, Segers P, Torck U, Hoste B, Bernardet JF, Vandamme P. et al. Reclassification of Flavobacterium odoratum (Stutzer 1929) strains to a new genus, Myroides, as Myroides odoratus comb. nov. and Myroides odoratimimus sp. nov.. Int J Syst Evol Microbiol 1996; 46: 926-32
- Benedetti P, Rassu M, Pavan G, Sefton A, Pellizzer G. Septic shock, pneumonia, and soft tissue infection due to Myroides odoratimimus: Report of a case and review of Myroides infections. Infection 2011; 39: 161-5
- Macfarlane DE, Baum-Thureen P, Crandon I. Flavobacterium odoratum ventriculitis treated with intraventricular cefotaxime. J Infect 1985; 11: 233-8
- Hu S, Cao L, Wu Y, Zhou Y, Jiang T, Wang L, Sarin YK. et al. Comparative genomic analysis of Myroides odoratimimus isolates. Microbiologyopen 2019; 8: e00634